Max-Planck-Institut für Informatik
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FunSimMat - Functional Similarity Matrix

FunSimMat is a comprehensive resource of semantic and functional similarity values. It allows ranking disease candidate proteins for OMIM diseases and searching for functional similarity values
for proteins (extracted from UniProt), and protein families (Pfam, SMART). FunSimMat provides several different semantic and functional similarity measures
for each protein pair using the Gene Ontology annotation from UniProtKB and the Gene Ontology Annotation project at EBI (GOA).
There are several search options available:

Disease candidate prioritization:

Functional similarity:

Semantic similarity:

Help page


Query FunSimMat

The query form can be found here.



If you have any questions, comments, suggestions, criticism, or encounter any problem with the web server feel free to contact us at: funsimmat [at] mpi-inf [dot] mpg [dot] de.